**José R. Zubizarreta**

Harvard Medical School

Professor, Department of Biostatistics

Harvard School of Public Health

Faculty Affiliate, Department of Statistics

Faculty of Arts and Sciences

Harvard University

**QUICK LINKS**:

Publications:

Edited volume

Articles, statistics

Articles, health

Software

Curriculum vitae

**EDITORIAL SERVICE**:

*Journal of the Royal Statistical Society, Series B*

Associate editor (2023-present),

*Annals of Applied Statistics*

Associate editor (2020-present),

*Biometrics*

Associate editor (2019-2024),

*Journal of Computational and Graphical Statistics*

Associate editor (2018-present),

*Observational Studies*

**PUBLICATIONS**:

:*Edited volume*Zubizarreta, J. R., Stuart, E. A., Small, D. S. and Rosenbaum, P. R., Editors (2023).

*Handbook of Matching and Weighting Adjustments for Causal Inference.*Chapman & Hall/CRC Press.

:*Articles, statistics*Cohn, E. R., Song, Z., and Zubizarreta, J. R. (2024), "Risk Set Matched Difference-in-Differences for the Analysis of Effect Modification in an Observational Study on the Impact of Gun Violence on Health Outcomes,"

, accepted.*Annals of Applied Statistics*

**Eric Cohn, winner of the American Statistical Association Health Policy Statistics Student Paper Award, 2024.*

Chattopadhyay, A., Cohn, E. R., and Zubizarreta, J. R. (2024), "One-Step Weighting to Generalize and Transport Treatment Effect Estimates to a Target Population,"

, accepted.*The American Statistician*

Kim, K., Niknam, B., and Zubizarreta, J. R. (2024), "Scalable Kernel Balancing Weights in a Nationwide Observational Study of Hospital Profit Status and Heart Attack Outcomes,"

, accepted.*Biostatistics*

Chattopadhyay, A., Greifer, N., and Zubizarreta, J. R. (2024), "lmw: Linear Model Weights for Causal Inference,"

, accepted.*Observational Studies*

Han, L., Li, Y., Niknam, B., and Zubizarreta, J. R. (2024), "Privacy-Preserving, Communication-Efficient, and Target-Flexible Hospital Quality Measurement,"

, 18, 1337–1359.*Annals of Applied Statistics*

**Larry Han, winner of the American Statistical Association Health Policy Statistics Student Paper Award, 2023.*

*Larry Han, winner of the Best Oral Student Paper Presentation, WNAR 2022.

Chattopadhyay, A., and Zubizarreta, J. R. (2024), "Causation, Comparison, and Regression,"

, 6.1.*Harvard Data Science Review*

Han, L., Shen, Z., and Zubizarreta, J. R. (2023), "Multiply Robust Federated Estimation of Targeted Average Treatment Effects,"

, 36.*Advances in Neural Information Processing Systems (NeurIPS)*

Chattopadhyay, A., and Zubizarreta, J. R. (2023), "On the Implied Weights of Linear Regression for Causal Inference,"

, 110, 615–629.*Biometrika*

**Ambarish Chattopadhyay, Dempster Prize, 2021 (awarded by the Department of Statistics at Harvard University)*

Kim, K., and Zubizarreta, J. R. (2023), "Toward Fair and Robust Estimation of Conditional Average Treatment Effects for Optimal Treatment Regimes,"

.*International Conference in Machine Learning (ICML)*

Díaz, J. D., and Zubizarreta, J. R. (2023), "Complex Discontinuity Designs Using Covariates: Impact of School Grade Retention on Later Life Outcomes in Chile,"

, 17, 67-88.*Annals of Applied Statistics*

Wang, Y., and Zubizarreta, J. R. (2023), "Large Sample Properties of Matching for Balance,"

, 33, 1-20.*Statistica Sinica*

Rosenbaum, P. R., and Zubizarreta, J. R. (2023), "Optimization Techniques in Multivariate Matching," in

, II, 63-86.*Handbook of Matching and Weighting Adjustments for Causal Inference*

Cohn, E. R., Ben-Michael, E., Feller, A., and Zubizarreta, J. R. (2023), "Balancing Weights for Causal Inference," in

, III, 293-312.*Handbook of Matching and Weighting Adjustments for Causal Inference*

Kim, K., Kennedy, E. H., and Zubizarreta, J. R. (2022), "Doubly Robust Counterfactual Classification,"

, 35.*Advances in Neural Information Processing Systems (NeurIPS)*

Cohn, E. R., and Zubizarreta, J. R. (2022), "Profile Matching for the Generalization and Personalization of Causal Inferences,"

, 33, 678-688.*Epidemiology*

**Eric Cohn, Young Investigator Award, 2021 (awarded by the American Statistical Association section on Statistics in Epidemiology)*

Niknam, B., and Zubizarreta, J. R. (2022), "Using Cardinality Matching to Design Balanced and Representative Samples for Observational Studies,"

, 327, 173–174.*Journal of the American Medical Association*Bennett, M., Vielma, J. P., and Zubizarreta, J. R. (2020), "Building Representative Matched Samples with Multi-valued Treatments in Large Observational Studies,"

, 29, 744–757.*Journal of Computational and Graphical Statistics*

**Magdalena Bennett, winner of the International Biometric Society ENAR Student Paper Award, 2019 (awarded by ENAR)*

Chattopadhyay, A., Hase, C., and Zubizarreta, J. R. (2020),"Balancing Versus Modeling Approaches to Weighting in Practice,"

, 39, 3227-3254.*Statistics in Medicine*

*-Download code*Resa. M. A., and Zubizarreta, J. R. (2020), "Direct and Stable Weight Adjustment in Non-Experimental Studies with Multi-valued Treatments: Analysis of the Impact of an Earthquake on Posttraumatic Stress,"

, 183, 1387-1410.*Journal of the Royal Statistical Society: Series A*Wang, Y., and Zubizarreta, J. R. (2020), "Minimal Dispersion Approximately Balancing Weights: Asymptotic Properties and Practical Considerations,"

, 107, 93-105.*Biometrika*

**Yixin Wang, winner of the Biometrics Student Paper Award, 2018 (awarded by the Biometrics Section of the American Statistical Association)*

Miratrix, L. W., Wager, S., and Zubizarreta, J. R. (2018),"Shape-Constrained Partial Identification of a Population Mean Under Unknown Probabilities of Sample Selection,"

, 107, 103-114.*Biometrika*

Visconti, G., and Zubizarreta, J. R. (2018), "Handling Limited Overlap in Observational Studies with Cardinality Matching,"

, 4, 217-249.*Observational Studies*

**Winner of the William Cochran prize for the best paper published in Observational Studies in 2015-2019*

Aronow, P. M., Crawford, F. W., and Zubizarreta, J. R. (2018),"Confidence Intervals for Linear Unbiased Estimators Under Constrained Dependence,"

, 12, 2238-2252.*Electronic Journal of Statistics*

Zubizarreta, J. R., Small, D. S., and Rosenbaum, P. R. (2018), "A Simple Example of Isolation in Building a Natural Experiment,"

, 31, 16-23.*Chance*

Haneuse, S., Zubizarreta, J. R., and Normand, S. L. T. (2018), "On Assessing the Quality of Health Care Providers Using Time-Varying Patient Outcomes,", invited commentary,

, 74, 1395-1397.*Biometrics*

Zubizarreta, J. R., and Keele. L. (2017), "Optimal Multilevel Matching in Clustered Observational Studies: A Case Study of the Effectiveness of Private Schools Under a Large-Scale Voucher System,"

, 112, 547-560.*Journal of the American Statistical Association*

Hirshberg, D. A., and Zubizarreta, J. R. (2017), "On Two Approaches to Weighting in Causal Inference," invited commentary,

, 28, 812-816.*Epidemiology*

Kilcioglu. C., and Zubizarreta, J. R. (2016), "Maximizing the Information Content of a Balanced Matched Sample in a Study of the Economic Performance of Green Buildings,"

, 10, 1997–2020.*Annals of Applied Statistics*

Resa. M. A., and Zubizarreta, J. R. (2016), "Evaluation of Subset Matching Methods and Forms of Covariate Balance,"

, 35, 4961–4979.*Statistics in Medicine*

Zubizarreta, J. R. (2015), "Stable Weights that Balance Covariates for Estimation with Incomplete Outcome Data,"

, 110, 910–922.*Journal of the American Statistical Association*

**Winner of the Biometrics Student Paper Award, 2014 (awarded by the Biometrics Section of the American Statistical Association)*

**Winner of the International Biometric Society ENAR Student Paper Award, 2014 (awarded by ENAR)*

Hsu. J., Zubizarreta, J. R., Small, D. S., and Rosenbaum, P. R. (2015), "Strong Control of the Family-Wise Error Rate in Observational Studies that Discover Effect Modification by Exploratory Methods,"

, 102, 767–782.*Biometrika*

Keele, L., Titiunik, R., and Zubizarreta, J. R. (2015), "Enhancing a Geographic Regression Discontinuity Design Through Matching to Estimate the Effect of Ballot Initiatives on Voter Turnout,"

, 178, 223–239.*Journal of the Royal Statistical Society: Series A*

Zubizarreta, J. R., Small, D. S., and Rosenbaum, P. R. (2014), "Isolation in the Construction of Natural Experiments,"

, 8, 2096–2121.*Annals of Applied Statistics*

Yang. F., Zubizarreta, J. R., Small, D. S., Lorch, S. A., and Rosenbaum, P. R. (2014), "Dissonant Conclusions When Testing the Validity of an Instrumental Variable,"

, 68, 253-263.*The American Statistician*

Zubizarreta, J. R., Paredes, R. D., and Rosenbaum, P. R. (2014), "Matching for Balance, Pairing for Heterogeneity in an Observational Study of the Effectiveness of For-profit and Not-for-profit High Schools in Chile,"

, 8, 204-231.*Annals of Applied Statistics*

**Winner of the Social Statistics, Government Statistics, and Survey Research Methods Sections Student Paper Award, 2013 (awarded by these three Sections of the American Statistical Association)*

*Zubizarreta, J. R., Cerdá, M., and Rosenbaum, P. R. (2013), "Designing an Observational Study to be Less Sensitive to Unmeasured Biases: Effect of the 2010 Chilean Earthquake on Posttraumatic Stress,"*, 24, 79-87 (with discussion).*Epidemiology*

**Winner of the*, 2014 (awarded for the best paper published in Epidemiology in 2013)*Kenneth Rothman Prize*

**Young Investigator Award, 2012 (awarded by the American Statistical Association section on Statistics in Epidemiology)*

Zubizarreta, J. R., Small, D. S., Goyal, N. K., Lorch, S. A., and Rosenbaum, P. R. (2013)," Stronger Instruments Via Integer Programming in an Observational Study of Late Preterm Birth Outcomes,"

, 7, 25-50.*Annals of Applied Statistics*

Zubizarreta, J. R. (2012), "Using Mixed Integer Programming for Matching in an Observational Study of Kidney Failure after Surgery,"

, 107, 1360-1371.*Journal of the American Statistical Association*

**Winner of the Deming Scholar Award, 2012 (awarded by the American Statistical Society and the American Society for Quality)*

Zubizarreta, J. R., Neuman, M. D., Silber, J. H., and Rosenbaum, P. R. (2012), "Contrasting Evidence Within and Between Institutions that Supply Treatment in an Observational Study of Alternative Forms of Anesthesia,"

, 107, 901-915.*Journal of the American Statistical Association*

**Winner of the Tom R. Ten Have Memorial Award, 2011 (awarded at the Atlantic Causal Inference Conference for "exceptionally creative or skillful research on causal inference")*

**Winner of the HPSS Student Paper Award, 2011 (awarded by the Health Policy and Statistics Section of the American Statistical Association)*

Zubizarreta, J. R., Reinke, C. E., Kelz, R. R., Silber, J. H., and Rosenbaum, P. R. (2011), "Matching for Several Sparse Nominal Variables in a Case-Control Study of Readmission Following Surgery,"

, 65, 229-238.*The American Statistician*

:**Articles, health**Song, Z., Zubizarreta, J. R., Giurato, M., Koh, K. A., and Sacks, C. A. (2023), "Firearm Injuries in Children and Adolescents: Changes in Health and Health Care Among Survivors and Family Members,"

, 42, 1541-1550.*Health Affairs*

Tang, M., Nakamoto, C. H., Stern, A. D., Zubizarreta, J. R., Marcondes, F. O., Uscher-Pines, L., Schwamm, L. H., and Mehrotra, L. (2023), "Effects of Remote Patient Monitoring Use on Care Outcomes among Medicare Patients with Hypertension,"

, 176, 1465-1475.*Annals of Internal Medicine*

Puac-Polanco, V., Ziobrowski, H. N., Ross, E. L., Liu, H., Turner, B., Cui, R., Leung, L. B.,Bossarte, R. M., Bryant, C., Joormann, J., Nierenberg, A. A., Oslin, D. W., Pigeon, W. R.,Post, E. P., Zainal, N. H., Zaslavsky, A. M., Zubizarreta, J. R., Luedtke, A., Kennedy, C.J., Cipriani, A., Furukawa, T. A., and Kessler, R. C. (2023), "Development of a Model to Predict Antidepressant Treatment Response for Depression among Veterans,"

, 53, 5001-5011.*Psychological Medicine*

Ziobrowski, H. N., Cui, R., Ross, E. L., Liu, H., Puac-Polanco, V., Turner, B., Leung, L. B., Bossarte, R. M., Bryant, C., Pigeon, W. R., Oslin, D. W., Post, E. P., Zaslavsky, A. M., Zubizarreta, J. R., Nierenberg, A. A., Luedtke, A., Kennedy, C. J., and Kessler, R. C. (2023),"Development of a Model to Predict Psychotherapy Response for Depression among Veterans,"

, 53, 3591-3600.*Psychological Medicine*

Bossarte, R. M., Ross, E. L., Liu, H., Turner, B., Bryant, C., Zainal N. H., Puac-Polanco, V., Ziobrowski, H. N., Cui, R., Cipriani, A., Furukawa, T. A., Leung, L. B., Joormann, J., Nierenberg, A. A., Oslin, D. W., Pigeon, W. R., Post, E. P., Zaslavsky, A. M., Zubizarreta, J. R., Luedtke, A., Kennedy, C. J., and Kessler, R. C. (2023), "Development of a Model to Predict Combined Antidepressant Medication and Psychotherapy Treatment Response for Depression among Veterans,"

, 326, 111-119.*Journal of Affective Disorders*

Li, Y., Undurraga, E. A., and Zubizarreta, J. R. (2022), “Effectiveness of Localized Lockdowns in the COVID-19 Pandemic,”

, 191, 812-824.*American Journal of Epidemiology*

**Yige Li, winner of the HPSS Student Paper Award, 2021 (awarded by the Health Policy and Statistics Section of the American Statistical Association)*

**Yige Li, winner of the International Biometric Society WNAR Student Paper Award, 2021 (awarded by WNAR)*

Niknam, B., and Zubizarreta, J. R. (2022), “Examining Sources of Post-Acute Care Inequities with Layered Target Matching,”

, 58, 19-29.*Health Services Research*Song, Z., Zubizarreta, J. R., Giuriato, M., Paulus, E., and Koh, K. A.(2022), “Changes in Health Care Spending, Utilization, and Morbidity After Nonfatal Firearm Injuries,”

, 175, 795-803.*Annals of Internal Medicine*

Wilcock, A. D., Schwamm, L. H., Zubizarreta, J. R.,Zachrison, K. S., Uscher-Pines, L., Majersik, J. J., Richard, J. V., and Mehrotra, A. (2022), “Impact of the FAST Act on Billing for Telemedicine,”

, 41, 350-359.*Health Affairs*

Jara, A., Undurraga, E. A., Zubizarreta, J. R., Gonzalez, C., Acevedo, J., Pizarro, A., Vergara, V., Flores, J. C., Suarez, P., Leighton, P., Eguiguren, P., Rios, J. C., Garcia-Escorza, H., and Araos, R. (2022), “Effectiveness of CoronaVac in Children 3 to 5 Years During the SARS-CoV-2 Omicron Outbreak in Chile,”

, 28, 1377-1380.*Nature Medicine*Wilcock, A. D., Schwamm, L. H., Zubizarreta, J. R., Zachrison, K. S., Uscher-Pines, L., Richard, J. V., and Mehrotra, A. (2022), “Reperfusion Treatment and Stroke Outcomes in Hospitals with Telestroke Capacity,”

, 78, 527-535.*Journal of the American Medical Association Neurology*

Jara, A., Undurraga, E. A., Zubizarreta, J. R., Gonzalez, C., Pizarro, A., Acevedo, J., Leo, K., Paredes, F., Bralic, T., Vergara, V., Mosso, M., Leon, F., Parot, I., Leigthon, P., Suarez, P., Rios, J.C., Garcia-Escorza, H., and Araos, R. (2022), “Effectiveness of Homologous and Heterologous Booster Shots for an Inactivated SARS-CoV-2 Vaccine: A Large Scale Observational Study,”

, 10, e798-e806.*Lancet Global Health*-
Ziobrowski, H.N., Cui, R., Ross, E.L., Liu, H., Puac-Polanco, V., Turner, B., Leung, L.B., Bossarte, R.M., Bryant, C., Pigeon, W.R., Oslin, D.W., Post, E.P., Zaslavsky, A.M., Zubizarreta, J.R., Nierenberg, A.A., Luedtke, A., Kennedy, C.J., andKessler, R.C. (2022), “Development of a Model to Predict Psychotherapy Response for Depression among Veterans,”

, 53, 3591-3600.*Psychological Medicine* Zubizarreta, J. R., Umhau, J. C.,Deuster, P., King, A.,Petukhova, M., Tizenberg, B., Upadhyaya, S. K., RachBeisel, J. A., Streeten, E., Kessler, R. C., and Postolache, T. T. (2022), “Evaluating the Heterogeneous Effect of a Modifiable Risk Factor on Suicide: The Case of Vitamin D Deficiency,”

, 31, e1897.*International Journal of Methods in Psychiatric Research*

Zachrison, K. S., Richard, J. V., Wilcock, A. D., Zubizarreta, J. R., Schwamm, L. H., Uscher- Pines, L., and Mehrotra, A. (2021), “Is Hospital Adoption of Telestroke Associated with Changes in the Stroke System of Care?,”

, 4, e2126612.*Journal of the American Medical Association, Network Open*

Gondi, S.,Wright, A. A., Landrum, M. B., Meneades L., Zubizarreta, J. R., Chernew, M .E., and Keating, N. L. (2021), “Assessment of Patient Attribution to Care from Medical Oncologists, Surgeons or Radiation Oncologists Following a New Cancer Diagnosis,”

, 4, e218055 .*Journal of the American Medical Association, Network Open*

Keating, N. L., Cleveland, J. L. F., Wright, A. A., Brooks G. A., Meneades L., Riedel L., Zubizarreta, J. R., Landrum, M. B. (2021), “Reliability and Correlations of Quality Measures for Oncology Cancer Care: Implications for Alternative Payment Models,”

, 4, e212474.*Journal of the American Medical Association, Network Open*

Leung, L. B., Ziobrowski, H. N., Puac-Polanco, V., Bossarte, R. M., Bryant, C., Keusch, J., Liu, H., Pigeon, W. R., Oslin, D. W., Post, E. P., Zaslavsky, A. M., Zubizarreta, J. R., and Kessler, R. C. (2021), “Are Veterans Getting their Preferred Depression Treatment? A National Observational Study in the Veterans Health Administration,”

, 37, 3235-3241.*Journal of General Internal Medicine*Ziobrowski, H. N., Leung, L. B., Bossarte, R. M., Bryant, C., Keusch, J., Liu, H., Puac- Polanco, V., Pigeon, W. R., Oslin, D. W., Post, E. P., Zaslavsky, A. M., Zubizarreta, J. R., and Kessler, R. C. (2021), “Comorbid Mental Disorders, Depression Symptom Severity, and Role Impairment Among Veterans Initiating Depression Treatment Through the Veterans Health Administration,”

, 290, 227-236.*Journal of Affective Disorders*

Patel, S. Y.,Huskamp, H. A., Barnett, M. L., Zubizarreta, J. R., Zachrison, K. S., Busch, A. B.,Wilcock, A. D., and Mehrotra, A.(2021), “Association between Telepsychiatry Capability and Treatment of Patients with Mental Illness in the Emergency Department,”

, 73, 403-410.*Psychiatric Services*

Kessler, R. C., Bossarte, R. M., Luedtke, A., Zaslavsky, A. M., and Zubizarreta, J. R. (2020), "Suicide Prediction Models: A Critical Review of Recent Research with Recommendations for the Way Forward,"

, 25, 168–179.*Molecular Psychiatry*

Kessler, R. C., Bossarte, R. M., Luedtke, A., Zaslavsky, A. M., and Zubizarreta, J. R. (2019), "Machine Learning Methods for Developing Precision Treatment Rules,"

, 120.*Behaviour Research and Therapy*

Gondi, S., Wright, A. A.,Landrum, M. B., Zubizarreta, J. R., Chernew, M. E., and Keating, N. (2019), "Multimodality Cancer Care and Implications for Episode Payments in Cancer,"

, 25, 537-538.*American Journal of Managed Care*

Hu, W., Chan, C. W., Zubizarreta, J. R., and Escobar, G. J. (2018), "An Examination of Early Transfers to the ICU Based on a Physiologic Risk Score,"

, 20, 531-549.*Manufacturing & Service Operations Management*

**Runner-up Ralph Gomory Best Industry Studies Paper Award, 2019 (awarded by the Industry Studies Association for research excellence across eight different journals)*

**Runner-up Pierskalla Best Paper Award, 2017 (awarded by the Health Applications Society of INFORMS for research excellence in the field of health care management science)*

**Finalist for the MSOM Student Paper Award, 2017 (awarded by the MSOM Society of INFORMS for papers judged to be the best in the field of operations management)*

Hu, W., Chan, C. W., Zubizarreta, J. R., and Escobar, G. J. (2018), "Incorporating Longitudinal Comorbidity and Acute Physiology Data in Template Matching for Assessing Hospital Quality: an Exploratory Study in an Integrated Health Care Delivery System,"

, 56, 448-454..*Medical Care*

Rosellini, A. J., Dussaillant, F., Zubizarreta, J. R., Kessler, R. C., and Rose, S. (2018), "Predicting Post-traumatic Stress Disorder Following a Natural Disaster,"

, 96, 15-22.*Journal of Psychiatric Research*

Zubizarreta, J. R., Lorch, S. A., Marshall, G., D’Apremont, I., and Tapia, J. L. (2016), "Effect of Prophylactic CPAP in Very Low Birth Weight Infants in South America,"

, 36, 629-634.*Journal of Perinatology*

Neuman, M. D., Rosenbaum, P. R., Ludwig, J. M., Zubizarreta, J. R., and Silber, J. H. (2014), "Anesthesia Technique, Mortality, and Length of Stay After Hip Fracture Surgery,"

, 311, 2508-2517.*Journal of the American Medical Association*

Kelz, R. R., Reinke, C. E., Zubizarreta, J. R., Wang, M.,Saynisch, P.,Even-Shoshan, O., Reese, P. P., Fleisher, L. A., and Silber, J. H. (2013), "Acute Kidney Injury, Renal Function, and the Elderly Obese Surgical Patient: A Matched Case-Control Study,"

, 258, 359-363.*Annals of Surgery*

Goyal, N. K., Zubizarreta, J. R., Small, D. S., and Lorch, S. A. (2013), "Length of Stay and Readmission Among Late Preterm Infants: An Instrumental Variable Approach,"

, 3, 7-15.*Hospital Pediatrics*

Reinke, C. E., Kelz, R. R., Zubizarreta, J. R., Mi, L., Saynisch, P., Even-Shoshan, O., Fleisher, L. A., and Silber, J. H. (2012), "Obesity and Readmission in Elderly Surgical Patients,"

, 152, 355-362.*Surgery*

**SOFTWARE**:

depinf: R package for statistical inference for means with constrained dependent observations. Joint work with Peter Aronow and Forrest Crawford.

designmatch: R package for the construction of optimally matched samples for randomized experiments and observational studies that are balanced by design. Joint work with Cinar Kilcioglu.

FSM: R package for randomized and balanced allocation of units to treatment groups using the Finite Selection Model (FSM). Joint work with Ambarish Chattopadhyay and Carl Morris.

lmw: R package for the construction and diagnostics of linear model weights. Joint work with Ambarish Chattopadhyay and Noah Greifer.

mipmatch: R package for optimal matching in observational studies using mixed integer programming.

*-See installation instructions*sbw: R package for stable balancing weights. Joint work with Yige Li. Contributors: Mohammed-Amine Allouah and Noah Greifer.

scbounds: R package for shape-constrained partial identification of a population mean under unknown probabilities of sample selection. Joint work with Luke Miratrix and Stefan Wager.

**CURRICULUM VITAE**: